Docs · OGN platform

GPU-native genomics operating system

From raw reads to GIAB-validated variant calls in a continuous GPU pipeline. This is the control surface for the engine: CLI, pipelines, benchmarks, and deployment runbooks.

CUDA 12+Hopper · AmpereGIAB-validated flowsSchemas stable

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GPU support matrix

Benchmark pack Example pipelines GitHub

OGN GPU Support Matrix

Minimum supported compute capability (CC): 7.0 (Volta) and newer.
Optimized targets (“fast path”):
- Ampere: CC 8.0, 8.6
- Ada/Lovelace: CC 8.9
- Hopper: CC 9.0 (DPX available)
DPX acceleration: Optional, Hopper+ only. Controlled by OGN_ENABLE_DPX_FASTPATH (CMake) and OGN_ENABLE_DPX (env, default on).
CPU fallback: Planned default for tests/CI via OGN_ENABLE_CPU_FALLBACK (CMake) and OGN_FORCE_BASELINE (env, forthcoming). Intended for environments without a GPU.
CUDA toolkit: 12.x recommended; tested primarily on 12.4–12.6 images.
Build architectures (fat binary default): 70;75;80;86;89;90. Override with -DCMAKE_CUDA_ARCHITECTURES= to slim builds if desired.

For production pipelines, prefer Ampere or newer. Hopper unlocks DPX fast paths; pre-Hopper devices run the baseline kernels.