Golden Drift Demo: CRISPR IP posture report
A public, downloadable demo bundle that proves the format: baseline → delta → posture, with forced interpretation guardrails and deterministic artifacts.
Not legal advice. Similarity alerts are not infringement/FTO conclusions.
Browse the PatentChecker demo set
Jump between live posture reports, delivery blocking analysis, and offline-verifiable proof bundles without backing out to the PatentChecker overview.
Vector blocking analysis across capsid overlap, licensing dependency, manufacturing sensitivity, and exclusivity zones.
Live posture report for sequence-watchlist drift: baseline, delta, open actions, and monitoring queues.
Downloadable drift packet with checksums, manifest verification, and contract-validated Evidence Packet JSON.
Verifiable runner-image quickstart for the signed PatentChecker evaluation path.
Replay-verifiable PTAB evidence bundle with decision metadata, captures, provenance, and verifier scripts.
Signed deterministic proof bundle for an engineering and procurement review workflow.
What you download
This archive is intentionally small and self-contained. It includes the executive report, a machine summary, and a contract-validated Evidence Packet JSON sample.
- report.md (exec-readable posture report)
- alerts_summary.json (machine recap, stable ordering)
- sample_evidence_packet.json (contract-validated Evidence Packet)
- watchlist-run-manifest.v0.1.json (alert + packet hash inventory)
- watchlist_state.v0.1.json (rolled-up posture/state)
- manifest.sha256 (verification of extracted files)
Screenshot (money shot)
One page you can forward internally: current posture with explicit triggers and recommended actions.
Contract-validated JSON (Evidence Packet)
This is a real Evidence Packet JSON from the demo (schema name/version declared in the payload). It includes interpretation guardrails and explicit fresh-look triggers.
View sample_evidence_packet.json
{
"alert": {
"alert_id": "alert|wl_demo_crispr_guide_001|run_2025-01-01T000000Z_demo_crispr_guide|US-CRISPR-FAM-001",
"dedup_key": "wl_demo_crispr_guide_001:US-CRISPR-FAM-001",
"diff_events": [
{
"current": {
"publication_number": "US2024000100"
},
"detected_at": "2025-01-01T00:00:00Z",
"event_type": "FAMILY.NEW_MEMBER_PUBLICATION",
"severity": "HIGH",
"subject": {
"family_id": "US-CRISPR-FAM-001",
"publication_number": "US2024000100"
}
},
{
"current": {
"roi_overlap_fraction": 0.4,
"roi_overlap_length": 7
},
"detected_at": "2025-01-01T00:00:00Z",
"event_type": "MATCH.ROI_OVERLAP_CHANGED",
"previous": {
"roi_overlap_fraction": 0.63,
"roi_overlap_length": 12
},
"severity": "HIGH",
"subject": {
"family_id": "US-CRISPR-FAM-001",
"query_seq_hash": "sha256:41c1bc31341a9ff9201d3d1155a39419b507d87b3ef939a884fb559a4ffddf69",
"target_seq_hash": "sha256:d0c0ff32cd06a3135e3e8dc88915f002fbafc278db5cd761d414260896f210d3"
}
},
{
"current": {
"publication_number": "US2024000100"
},
"detected_at": "2025-01-01T00:00:00Z",
"event_type": "PUB.NEW_PUBLICATION_FOR_TARGET",
"severity": "HIGH",
"subject": {
"family_id": "US-CRISPR-FAM-001",
"publication_number": "US2024000100",
"target_seq_hash": "sha256:d0c0ff32cd06a3135e3e8dc88915f002fbafc278db5cd761d414260896f210d3"
}
}
],
"family_id": "US-CRISPR-FAM-001",
"fresh_look_triggers": [
"new_publication",
"roi_overlap_delta"
],
"severity": "HIGH"
},
"attachments": [],
"corpus": {
"snapshots": [
{
"content_hash": "sha256:4362eee9cfbdfc4998071437c55b973ed5f194145db7862a900cd67fa3b1e22c",
"jurisdictions": [
"US"
],
"made_public_until": "2025-01-01",
"notes": "USPTO granted + applications; claim text + sequence listings.",
"sequence_types": [
"NT"
],
"snapshot_id": "uspto_us_2015-2025_2025-01-01",
"source": "uspto_us"
}
]
},
"engine": {
"name": "mmseqs2",
"parameters": {
"min_identity": 0.6,
"mode": "nt",
"sensitivity": 7.5
},
"parameters_hash": "sha256:f115281bcf3d9271e2290a11f33bf88b7cdad10d653c6deb780cd7357afe0c78",
"version": "demo"
},
"extensions": {},
"generated_at": "2025-01-01T00:00:00Z",
"hits": [
{
"alignment": {
"identity": 0.95,
"query_coverage": 1,
"query_end": 19,
"query_start": 1,
"target_end": 19,
"target_start": 1
},
"band": "HIGH",
"publications": [
{
"assignees": [
"Broad Institute, Inc."
],
"family_id": "US-CRISPR-FAM-001",
"jurisdiction": "US",
"publication_date": "2021-06-01",
"publication_number": "US2021000001",
"title": "CRISPR guide RNA targeting compositions"
},
{
"assignees": [
"Broad Institute, Inc."
],
"family_id": "US-CRISPR-FAM-001",
"jurisdiction": "US",
"publication_date": "2024-10-01",
"publication_number": "US2024000100",
"title": "Guide RNA variants and targeting strategies"
}
],
"roi_overlaps": [
{
"overlap_fraction": 0.4,
"overlap_length": 7,
"roi_id": "roi1"
}
],
"target": {
"length": 19,
"seq_hash": "sha256:d0c0ff32cd06a3135e3e8dc88915f002fbafc278db5cd761d414260896f210d3",
"seq_type": "NT"
}
}
],
"interpretation_guardrails": [
"Match indicates similarity under configured method",
"Outputs are informational; not legal advice",
"Not an infringement or Freedom-to-Operate (FTO) determination",
"Claim scope review required before action"
],
"packet_id": "f7619574-41c1-5de3-bddf-4b3f01993947",
"query": {
"length": 19,
"regions_of_interest": [
{
"end": 19,
"kind": "FUNCTIONAL",
"roi_id": "roi1",
"start": 1
}
],
"seq_hash": "sha256:41c1bc31341a9ff9201d3d1155a39419b507d87b3ef939a884fb559a4ffddf69",
"seq_type": "NT"
},
"run": {
"previous_run_id": "run_2024-01-01T000000Z_demo_crispr_guide",
"run_at": "2025-01-01T00:00:00Z",
"run_id": "run_2025-01-01T000000Z_demo_crispr_guide"
},
"schema_name": "patentchecker.evidence_packet",
"schema_version": "0.1",
"watchlist": {
"name": "CRISPR Guide RNA Demo",
"threshold_profile": {
"high": {
"identity_min": 0.9,
"query_coverage_min": 0.8
},
"low": {
"identity_min": 0.6,
"query_coverage_min": 0.4
},
"medium": {
"identity_min": 0.8,
"query_coverage_min": 0.6
},
"min_band": "LOW",
"roi": {
"overlap_fraction_min": 0.5,
"overlap_length_min": 0
}
},
"watchlist_id": "wl_demo_crispr_guide_001"
}
}Download & verify
# download curl -LO https://omnisgenomics.com/patent-checker/proof/patentchecker-golden-drift-demo-v0.1.26.tar.gz curl -LO https://omnisgenomics.com/patent-checker/proof/patentchecker-golden-drift-demo-v0.1.26.tar.gz.sha256 # verify the archive sha256sum -c patentchecker-golden-drift-demo-v0.1.26.tar.gz.sha256 # extract tar -xzf patentchecker-golden-drift-demo-v0.1.26.tar.gz cd golden_drift_demo # verify extracted contents sha256sum -c manifest.sha256